Non-Peer Reviewed Scientific and Medical Publications

Proceedings of Meetings, Research Publications

1. Hochberg F, Schonberger L and McGowan J.
Human Mercury Exposure A Symposium. Center for Disease Control, 1971.

2. Hochberg F.
Organic Mercury Related Neurologic Disease in the Western Environment. Oregon State University, Portland, 1971.

3. Schonberger L, Creech W, McGowan J, Hochberg F.
Poliomyelitis. Center for Disease Control, 1973.

4. DeVeber G and Hochberg FH.
Determinants of Prognosis in Brainstem Glioma. Neurosurgeons (Japan) (Proceedings of the Japan Neurosurgical Society). 10:49-54, 1991.


1. Hochberg F, Safdari H and Rabinowicz T.
Histologic correlates of survival in malignant gliomas. Acta Neurochir [suppl] 28(2):485-488, 1979.

2. Beck D and Hochberg F.
Rationale for preirradiation chemotherapy in treatment of malignant gliomas. J. Neurosurg. 63:994-996, 1985.

3. Bashir R and Hochberg FH.
Pre-irradiation internal carotid artery BCNU for treatment of malignant gliomas. J. Neurosurg. (suppl 1) 37, 1987.

4. Hochberg FH and Miller D.
Primary Central Nervous System Lymphoma. J. Neurosurg 68:835-853, 1988.

5. Hochberg FH.
Modalities of Cisplatin Administration to Brain Tumors. Cancer Investigation 7(6):611-612, 1989.

6. Hochberg FH, Harris SU, Blattert TR.
Occupational Hand Cramps: Professional Disorders of Motor Control. Hand Clinics of North America 6(3):417-428, 1990.

7. Michael L. Gruber and Fred H. Hochberg
(Invited) Editorial: Systematic Evaluation of Primary Brain Tumors. Jnl Nuclear Med. 31: 969-971, 1990.

8. Hochberg FH, Loeffler JS and Prados M.
The Therapy of Primary Brain Lymphoma. Jnl. Neuro-Oncol. 10:191-201, 1991.

9. Shapiro WR, Green SB, Nurger PC, Selker RG, Mahaley MS, Mealey J, Robertson JT, Hochberg FH, et al.
Recent Clinical Results in the Chemotherapy of Brain Tumors: BTCG Studies. Dev. Oncol. 66:147-52, 1991.

10. Hochberg F.
Imaging of brain tumors. Cancer 12:3080-82, 1994.

11. Hochberg FH and Cher L.
Primary Central Nervous System Lymphoma. (Review of DeAngelis article.) Oncology. 9(1):76-77, 1995.

12. Hochberg F and Das A.
Review of Contemporary Neurology: Neurologic Complications of Cancer. Oncology 45 (10): 185, 1996.

13. Damek DM, Hochberg FH.
Clinical aspects of brain tumor. Curr Opin Neurol. 10(6): 452-8, 1997.

14. Deshmukh, A, Scott JA, Palmer EL., Hochberg FH, Gruber M, Fischman AJ.
Impact of Fluorodeoxyglucose Positron Emission Tomography on the Clinical Management of Patients with Glioma. Clin Nucl. Med. 21:720-25, 1996.

15. Aghi M, Hochberg F, Breakefield XO.
Prodrug activating enzymes in cancer gene therapy. J Gene Medicine. 2000, 2(3):148-64.

16. Reni M, Ferrei AJM, Guha-Thakurta N, Blay JY, Dell’Oro S, Villa E, Hochberg FH.
Therapeutic issues in primary central nervous system lymphoma (PCNSL) with upfront high-dose methotrexate (>1 g/m2 HD-MTX). Int J Radiat Oncol Biol Phys. 2001, 1;51(2):419-25.

17. Hochberg FH, Tabatabai G.
Therapy of PCNSL at the Massachusetts General Hospital with high dose methotrexate and deferred radiotherapy. [Review] [5 refs] Annals of Hematology. 80 Suppl 3:B111-2, 2001.

18. Benjamin R, Hochberg F.
Microdialysis in Human Brain Tumors from Concept to Application. Neuro-Oncology, 2003.

19. Baehring JM, Longtine J, Hochberg F.
A New Approach to the Diagnosis and Treatment of Intravascular Lymphoma. Journal of Neuro-Oncology 2003.

20. Kirsch DG, Hochberg FH.
Targeting Her2 in brain metastases from Breast Cancer. Clin. Cancer Res. 9, 2003.

21. Hochberg FH, Baehring JM, Hochberg EP.
Primary CNS lymphoma. [Review] [85 refs] Nature Clinical Practice Neurology. 3(1):24-35, 2007.

22. Baehring JM, Hochberg EP, Raje N, Ulrickson M, Hochberg FH.
Neurological manifestations of Waldenstrom macroglobulinemia. [Review] [92 refs] Nature Clinical Practice Neurology. 4(10):547-56, 2008.

23. Pe’er J, Hochberg FH, Foster CS.
Treatment of Vitreal Lymphoma, A Review; Journal of Ocular Immunology and Inflammation. 2009

24. Hochberg N, Hochberg FH.
Eosinophilic Meningitis. European Jnl Infectious Disease, 2009.

25. Hochberg FH, Atai NA, Gonda D, Hughes MS, Mawejje B, Balaj L, Carter BS.
Glioma diagnostics and biomarkers: an ongoing challenge in the field of medicine and science. Expert Rev Mol Diagn 14(4):439-52, 2014


1. Hochberg F.
“Glioblastoma.” Chapter 32, Section II, pages 128-32 in Prognosis, Contemporary outcomes of Disease. James F. Fries, M.D. and George E. Ehrlich, M.D. (eds.), The Charles Press Publishers, 1981.

2. Hochberg F.
“Neurological aspects of systemic tumors” in Principles of internal medicine. Update I, Isselbacher, Adams, Braunwald, Petersdorf, Wilson and Martin (eds.), 9th edition, 10th edition, 11 edition, 12 edition, 13 edition. McGraw-Hill Co., New York, 1981-1993.

3. Takvorian T, Hochberg F, Canellos F, Parker L, Zervas N and Frei E.
“The toxicity of high-dose BCNU with autologous marrow support” in Nitrosoureas: Current Status and New Developments. Prestakyo, A.W., et al. (eds.), Academic Press Inc., New York, NY, 1981.

4. Hochberg F and Forman A.
“Central Nervous System Lymphoma” in Your Patient and Cancer. p.27, 1983.

5. Fingert H and Hochberg F.
“Megadose chemotherapy with Bone marrow rescue” in Progress in experimental brain tumor research. Rosenblum, M.D. and Wilson, C.B. Vol. 2:67-78, (Karger, Basel), 1984.

6. Jennings M, Gelman R and Hochberg F.
“Intracranial germ cell tumors: Natural History and Pathogenesis” in Diagnosis and Treatment of Intracranial Brain Cell Tumors. Neuwald, E.A. (ed.) Williams and Wilkins, Baltimore, 1984.

7. Hochberg F, Pruitt A. Beck DO, DeBrun, G, Davis K.
The rationale and methodology for intra-arterialchemotherapy with BCNU as treatment for glioblastoma” in Infusional therapies in cancer treatment. Howell, ST M. Nijhoff (Boston), 1984.

8. Krull IS, Ding XD, Selavka C, Hochberg F.
“Liquid Chromotographic determinations of Cis platinum Anti-surveys” in Biochemistry and analysis (Vol 14) edit E.Reid. Plenum Press, London. 1985.

9. Hochberg, F., Heros, D.
“Regional Infusion For Brain Tumors” in Cancer Chemotherapy by Infusion, Lokich J. Chap 36:467-78, 1987.

10. Heros D, Hochberg F.
“Intraventricular Chemotherapy for Leptomeningeal Carcinoma” in Cancer Chemotherapy by Infusion, Lokich J. Chap 39:525-37, 1987.

11. Hochberg FH, Lavin, Portney, Roberts D, Tinney C, Hottleman K, Wanger F, Newmark J, Cavanaugh K, Noonan M.
“Topical therapy of localized inflammation in musicians: A clinical evaluation of Aspercreme vs. Placebo” in Schmerz und Sport. Spintge and Droh (eds) pp: 135–49, 1988.

12. Hochberg FH, Lederman RJ.
“The Upper Extremity Difficulties of Musicians” in Rehabilitation of the Hand. Hunter JM. CV Mosby St. Louis, 1989) 99:1197-1209, 1990, 1993.

13. Hochberg FH and Gabbai AA.
“Risk Factors in the Development of Glioblastoma and Other Brain Tumors” in Neurosurgical Update (Wilkins Ed). 8:1, 1990.

14. Hochberg FH, Harris SU and Blattert T.
“Occupational Hand Cramps – Professional Disorders of Motor Control” in Hand Clinics of North America (Amadio Ed.). 6:417-28, 1990.

15. Hochberg FH and Gruber ML.
“Primary Central Nervous System Lymphoma” in Current Therapy in Neurologic Disease-4. (Johnson and Griffin Ed). 1993.

16. Chu N-S, Hochberg FH, Calne D and Olanow CW.
“Neurotoxicology of Manganese” in Handbook of Neurotoxicology (Chang LW and Dyer RS.). Dekker, New York 1995.

17. Hochberg FH and Pruitt AA.
“Tumors of the Nervous System” in Textbook of Internal Medicine (Harrison). Edit 10-13, 1994. (Edit. Isselbacher K).

18. Rock JP, Cher L, Hochberg FH, Rosenblum ML.
“Primary Central Nervous System Lymphoma” in Neurosurgery, 1995 (Youmans). Black PM and Loeffler J. 1995.

19. Huang CC, Lu CS, Chu NS, Hochberg FH, Lilienfeld D and Calne DB.
Pathogenesis of Idiopathic Parkinsonism in Rinne UK, Yanagisawa N. Controversies in the Treatment of Parkinson’s Disease. 7–13, 1992. (PMSI Japan, Tokyo.)

20. Brouillet E, Jenkins B, Michel R, Hochberg FH.
In Vivo Quantification of Cerebral Manganese Concentrations using Magnetic Resonance Imaging. Proceedings of the First International Manganese Conference, Chantilly, France. 1992.

21. Valenzuela R, Hochberg FH.
“Methotrexate Toxicity” in Experimental and Clinical Neurotoxicology. (Spencer and Schaumberg). Oxford Press 1996.

22. Cher L, Henson J, Hochberg FH.
“The Paraneoplastic Syndrome” in Handbook of Clinical Neurology, Systemic Diseases (Aminoff). Part III, Elsevier 1998.

23. Valenzuela R and Hochberg FH.
“Low Grade Gliomas”, Chapter 150, Section 2 in Office Practice of Neurology (Samuels et al). Churchill Livingston, New York, 1996.

24. Das A and Hochberg FH.
Metastatic Neoplasms and Paraneoplastic Syndromes in Goetz CG and Pappert EJ. Textbook of Clinical Neurology, WB Saunders, Phila. 1999.

25. Hochberg FH and Das A.
“Contemporary Neurology: Neurologic Complications of Cancer” Volume 45. Book Review. Oncology Vol 10:185, 1996.

25. Das A and Hochberg FH.
“Clinical presentation of intracranial metastases” in Neurosurgery Clinics of North America Volume 7, Number 3, 377-91, 1996.

26. Hochberg FH and Hochberg NS.
Occupational Cramps/focal dystonias in Tubiana and Amadio: Medical Problems of the instrumentalist musician, M. Dunitz, London 1999.

27. Baehring J, Schlegel U, Fred H. Hochberg.
Primary CNS Lymphoma in Jörg-Christian Tonn, Stuart A. Grossman, James T. Rutka and Manfred Westphal Neuro-Oncology of CNS Tumors, Springer Berlin Heidelberg 2006 and 2010.

Books/Textbooks for the Medical or Scientific Community

1. Rottenberg D.A. and Hochberg F. eds.
Neurologic Classics in Modern Translation. Hafner Press, Macmillan, June 1977.

2. Hochberg FH, Perkin GD, Miller DC.
Atlas of Clinical Neurology. Gower (London) 1992, 1994.

Case Reports

1. Rosman NP, Hochberg F, Richardson EP Jr.
Coma in a 13 year old girl (SSPE) Case Records of the Massachusetts General Hospital .New Eng J Med 291:141-49, 1974.

2. Picard E, Richardson EP Jr., Hochberg F.
Progressive obtundation in a 43 year old man. Case Records of Massachusetts General Hospital. New Eng J Med 290:1130-36, 1974.

News Media

Letters to the Editor

1. Bakshi R, Ducatman A, Hochberg FH.
Glioblastoma in New England Ophthalmologists. (Letter) NEJM 324:1440-41, 1991.

Clinical Guidelines and Reports

I have worked to provide the NCCN guidelines for brain tumor patient care and the Progress Review guidelines for the NCI sponsored PRG for Brain Tumors

1. Hildebrand J, Thomas DGT et al. (F. Hochberg as participant).
Report of a Workshop Sponsored by the European Organisation for Research and Treatment of Cancer (EORTC) on the Treatment of Primary Malignant Brain Tumours. Jnl Neuro. Neurosurg and Psych. 54:182-183, 1991.

2. Lener T et al.
Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper. JEV 2015.

3. Lotvall J, Hill A, Hochberg FH.
Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles JEV, 2014.


1. Hochberg FH; Supko J et al.
Phase I Study of Oral Gimatecan in Recurrent Glioblastoma, ASCO 2007.

2. N.U. Lin, L.A. Carey, M.C. Liu, J. Younger, S. Come, E. Bullitt, A van den Abbeele, R. Gelman, F. Hochberg, E.P. Winer.
Phase 2 Trial of Lapatinib for Brain Metastases in Patients with HER2+ Breast Cancer. ASCO 2007.

3. Hochberg FH, Fintleman F, Hochberg, E.
Bing-Neel Syndrome. Fifth Proceedings of the Waldenstroms Society, Stockholm 2008.

4. J. Hu, P. Y. Wen, L. Abrey, C. Fadul, J. Drappatz, N. Salem, A. Amato, P. Carminati, J. Supko, F. Hochberg.
Phase II trial of oral gimatecan in adults with recurrent glioblastoma. ASCO 2009.

5. Elizabeth R. Gerstner, Fred H. Hochberg, Scott R. Plotkin, April F. Eichler, Tracy T. Batchelor.
High-dose methotrexate, rituximab, and temozolomide (M/R/T) for patients with primary CNS lymphoma (PCNSL), American Society of Hematology 2009.

6. J Skog, B Carter, LD Zhu,  R Lessard, A Sahin, XO Breakefield, FH Hochberg*
Identification of  exosomal RNA levels of Epidermal Growth Factor From the sera of patients with glioblastoma. European Federation of Neurological Societies; Florence 2009.

7. Subramanian SL, Hochberg FH. ISEV 486 Bethesda 2015.
The exRNA Biospecimen virtual Repository: The CSF working Group Demonstration Project (and NIH exRNA meeting November 2014).

8. JP Nolan1, E Duggan1, J Akers2, K van-Keuren Jensen3, M Huentelman3, R Reiman3, JI Phillips4, JA Saugstad4, JF Quinn4, D Galasko2, BS Carter2, F Hochberg2.
Diversity of Extracellular Vesicles in exRNA-containing Biofluids Measured by Vesicle Flow Cytometry ISEV 2016 Rotterdam.